High blood pressure is often described as a “silent condition” — many people live with it for years before symptoms appear. While medication, diet and exercise remain the cornerstone of blood pressure management, growing scientific interest has turned towards the nervous system’s role in cardiovascular regulation, particularly the vagus nerve.
Introduction: Why the Vagus Nerve Matters More Than You Think
The vagus nerve is the body’s main pathway for calming signals. It plays a central role in regulating heart rate, blood pressure, inflammation and stress responses. Research suggests that reduced vagal activity (often called low vagal tone) is associated with higher cardiovascular risk, poorer stress resilience and adverse metabolic outcomes.
This article explains what the vagus nerve does, how it influences blood pressure, what the evidence says about vagus-stimulating practices, and how these approaches may fit — safely and realistically — into a broader cardiovascular and bone-health strategy.
Understanding the Vagus Nerve and the Autonomic Nervous System

The vagus nerve is the longest cranial nerve in the body, extending from the brainstem to the heart, lungs, digestive system and beyond. It is a major component of the autonomic nervous system, which regulates involuntary bodily functions.
Two key branches of the autonomic nervous system:
- Sympathetic nervous system
Often called the “fight or flight” system. It increases heart rate, blood pressure and alertness during stress. - Parasympathetic nervous system
Known as the “rest and digest” system. It slows the heart rate, supports digestion, and promotes recovery and repair.
The vagus nerve is the primary driver of parasympathetic activity. When it is functioning well, it helps counterbalance excessive sympathetic activation — a common feature in chronic stress and hypertension.
How the Vagus Nerve Influences Blood Pressure
Scientific studies show that vagal stimulation affects blood pressure through several mechanisms:
1. Heart rate regulation
Activation of the vagus nerve sends inhibitory signals to the heart, reducing heart rate. A slower heart rate typically lowers blood pressure because the heart pumps less forcefully.
2. Vascular tone
Parasympathetic signalling influences blood vessel dilation, helping vessels relax rather than remain constricted — another factor contributing to lower blood pressure.
3. Stress hormone modulation
Increased vagal tone is associated with reduced activity of stress hormones such as cortisol and adrenaline, which otherwise elevate blood pressure over time.
Low vagal tone has been linked to:
- Hypertension
- Increased cardiovascular risk
- Chronic inflammation
- Reduced stress resilience
Can Vagus Nerve Stimulation Lower Blood Pressure?
What the Evidence Actually Says
It is important to be clear: vagus nerve exercises are not a replacement for medical treatment. However, evidence suggests they may act as a supportive strategy alongside standard care.
Evidence-supported techniques include:
1. Slow, diaphragmatic breathing
Controlled breathing (around 5–6 breaths per minute) has been shown to:
- Increase vagal tone
- Reduce sympathetic nervous system activity
- Lower resting heart rate and blood pressure
Clinical studies demonstrate measurable reductions in systolic blood pressure when practised regularly.
2. Mindfulness and meditation
Mindfulness-based stress reduction (MBSR) programmes are associated with:
- Improved heart rate variability (a marker of vagal tone)
- Lower perceived stress
- Modest but consistent blood pressure reductions
3. Cold facial exposure (diving reflex)
Brief exposure of the face to cold water activates the diving reflex, mediated by the vagus nerve. This causes:
- Slowing of heart rate
- Temporary reduction in blood pressure
This effect is short-lived but physiologically well-documented.
4. Vocal stimulation: humming, singing, gargling
The vagus nerve innervates muscles of the throat and vocal cords. Activities involving vibration and prolonged exhalation may enhance parasympathetic activation.
Evidence here is modest but biologically plausible and low-risk.
Clinical Perspective: Where These Techniques Fit
From a medical standpoint, vagus nerve stimulation techniques should be viewed as:
- Adjunctive, not primary, interventions
- Most useful for stress-related or borderline hypertension
- Supportive of overall cardiovascular and inflammatory health
They do not replace:
- Blood pressure monitoring
- Lifestyle interventions (diet, physical activity, sleep)
- Prescribed antihypertensive medications when indicated
Patients with persistent or severe hypertension should always seek professional medical guidance.
Why This Matters for Bone Health
At London Osteoporosis Clinic, we recognise that bone health does not exist in isolation.
Chronic stress, inflammation and poor cardiovascular health can negatively influence:
- Bone remodelling
- Muscle strength
- Fall risk
- Fracture recovery
Improving autonomic balance through stress reduction may indirectly support:
- Better hormonal balance
- Reduced inflammatory burden
- Improved adherence to exercise and nutrition plans
This aligns with LOC’s holistic, prevention-focused philosophy.
Practical Takeaways
✔ The vagus nerve plays a key role in regulating heart rate, blood pressure and stress responses
✔ Reduced vagal tone is associated with higher cardiovascular risk
✔ Simple practices such as slow breathing and mindfulness can modestly improve vagal activity
✔ These techniques work best alongside, not instead of, standard medical care
✔ Managing stress and autonomic health supports both cardiovascular and bone health
When to Seek Professional Advice
If you experience:
- Persistently elevated blood pressure
- Dizziness, palpitations or fainting
- Significant anxiety or stress affecting daily life
A personalised assessment is essential.
👉 Book a consultation at London Osteoporosis Clinic to discuss cardiovascular health, inflammation, bone density and preventive strategies tailored to you.